GREEN LUKE,JAESCHKE GEORG,LINDERMANN LOTHAR,RUEHER DANIEL,VIEIRA ERIC,GUBA WOLFGANG,JOLIDON SYNESE,RICCI ANTONIO,STADLER HEINZ
申请号：
ZA201207285
公开号：
ZA201207285B
申请日:
2012.09.28
申请国别(地区):
ZA
年份:
2013
代理人:
摘要：
The present invention relates to ethynyl compounds of formula I wherein R1, R2, R2&prime；, R3, R3&prime；, R4, R4&prime；, U, V, W, Y, m, and n are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. Compounds of formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
