Zhiqiang An;Louis Jerry Fabri;Manuel Baca;William R. Strohl;Andrew Donald Nash;Dennis Zaller
发明人:
Andrew Donald Nash,Manuel Baca,Louis Jerry Fabri,Dennis Zaller,William R. Strohl,Zhiqiang An
申请号：
US12774966
公开号：
US08568722B2
申请日:
2010.05.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
High affinity antibody antagonists of human interleukin-13 receptor alpha 1 are disclosed. The antibody molecules are effective in the inhibition of IL-13Rα1-mediated activities and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with hIL-13Rα1 activity. The present invention also discloses nucleic acid encoding said antibody molecules, vectors, host cells, and compositions comprising the antibody molecules. Methods of using the antibody molecules for inhibiting or antagonizing IL-13Rα1-mediated activities are also disclosed.
