Xiping Liu;Jian Gong;Adrian Ion Bot;Chih-Sheng Chiang;Kent Andrew Smith;David C. Diamond;Zhiyong Qiu;Liping Liu
发明人:
Adrian Ion Bot,Chih-Sheng Chiang,David C. Diamond,Jian Gong,Kent Andrew Smith,Liping Liu,Xiping Liu,Zhiyong Qiu
申请号:
US13336523
公开号:
US20120148613A1
申请日:
2011.12.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a method of treating a cell proliferative disease such as cancer by providing to a subject in need thereof an immunogenic composition comprising plasmid and peptide(s) or analogues thereof. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.