Aqueous pharmaceutical formulations with an insulin analog, comprising 0.001 to 0.2 mg/ml of zinc, 0.1 to 5.0 mg/ml of a preservative, and 5.0 to 100 mg/ml of an isotonicity agent, and whose pH is 5 or less, and also their preparation, use for treating diabetes mellitus, and a medicament for treating diabetes mellitus.