Methods for treating neuropathic pain caused by a traumatic spinal cord injury are described. A method comprising administering an effective amount of flubendazole, an α-tubulin acetylation inhibitor, an endosomal NR1 and pERK1/2 inhibitor, a mitochondrial cyclin b1 inhibitor, a microtubule destabilizing drug, or combinations thereof to the patient suffering from the traumatic spinal cord injury. Also described is a method for preventing neuropathic pain in a patient with a spinal cord injury at risk for developing neuropathic pain comprising administering administrating an effective amount of flubendazole to a patient with the spinal cord injury at risk of developing neuropathic pain.