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Stabilised MRNA with an increased G/C content and optimised codon for use in gene therapy
专利权人:
Curevac GmbH
发明人:
von der Mulbe, Florian,Hoerr, Ingmar,Pascolo, Steve
申请号:
AU2009202873
公开号:
AU2009202873B2
申请日:
2009.07.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2009202873B220120816.pdf#####74 Abstract Pharmaceutical Composition containing a stabilised mRNA 5 optimised for translation in its Coding Regions The present invention relates to a pharmaceutical composition containing an mRNA that is stabilised by sequence modifications in the translated region and is 10 optimised for the translation. The pharmaceutical composition according to the invention is particularly suitable as an inoculating agent as well as a therapeutic agent for tissue regeneration. In addition a process is described for determining sequence modifications that serve 15 for the stabilisation and translation optimisation of mRNA.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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