TZENG, CHERNG CHYI,曾诚齐,曾誠齊,CHEN, YEH LONG,陈义龙,陳義龍,WANG, GWO JAW,王国照,王國照,HO, MEI LING,何美泠,CHANG, JE KEN,张瑞根,張瑞根,FU, YIN CHIH,傅尹志
申请号：
TW097106587
公开号：
TWI365071B
申请日:
2008.02.26
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
An isoxazole derivative is provided. The isoxazole derivative has following formula: wherein R1, R2, R3, R4 and R5, independently, include hydrogen, hydroxy or C1-C12 alkoxy optionally substituted with oxirane, thiirane, aziridine, amino, cycloamino, aminohydroxy or cycloaminohydroxy. The invention also provides a pharmaceutical composition for treatment of osteoporosis and cancer including an isoxazole derivative or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.本發明提供一種異唑衍生物，具有下列化學式：其中R1、R2、R3、R4及R5獨立地包括氫、羥基或C1－C12烷氧基，該C1－C12烷氧基選擇性地取代有環氧基、噻喃基、氮丙啶基、胺基、環胺基、胺基羥基或環胺基羥基。
