Anna Tampieri,Simone Sprio,Andrea Ruffini,Julia Will,Peter Greil,Frank Muller,Julian Martinez Fernandez,Carmen Torres Raya,Francisco Manuel Varela Feria,Joaquin Ramirez Rico,Marie-Francoise Harmand
申请号：
US13884123
公开号：
US20140134258A1
申请日:
2011.11.08
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a bone substitute comprising a core based on hydroxyapatite (HA), obtained from at least one porous wood, or based on collagen fibres and hydroxyapatite, and a shell, based on hydroxyapatite (HA) or silicon carbide (SiC), obtained from at least one wood having a lower porosity than the at least one wood of the core. The porous wood has a total porosity of between 60% and 95%, preferably between 65% and 85%, and it is selected from amongst the choices of rattan, pine, abachi and balsa wood. The wood of the shell has a porosity of between 20% and 60%, preferably between 30% and 50%. The bone substitute is utilized for the substitution and regeneration of bone, preferably for bones subjected to mechanical loads, such as long bones of the leg and arm, preferably the tibia, metatarsus, femur, humerus or radius.
