A method and system for acquiring data for assessment of cardiovascular disease, the method comprising one or more of: manipulating one or more hardware aspects of the photoplethysmography data acquisition system(s) implementing the method； manipulating or providing user experience/user interface (UX/UI) aspects of the system(s) implementing the method； acquiring, processing, and deriving insights population specific data； accounting for or controlling sampling site variability； and using other suitable sources of data in order to generate high quality data for characterization, assessment, and management of cardiovascular disease.
