Various self-cinching suture anchors and self-cinching suture anchor systems are provided. In one exemplary embodiment, a suture anchor 10 is provided that includes an outer member 14 and an inner member 16 configured to be received within the outer member. The inner and outer members can define a gap 20 that allows a suture 12 to be movably disposed within the outer member, e.g., within the gap, when the inner member is disposed within the outer member. The inner member can be configured to be secured within the outer member by a knot 26 of the suture having a diameter greater than a width of the gap so as to fix the inner member within the outer member, while still allowing uni-directional tensioning of the suture.