INSTITUTE OF BASIC MEDICAL SCIENCES; CHINESE ACADEMY OF MEDICAL SCIENCES
发明人:
Yanyong LIU,Nan YANG,Pingping ZUO
申请号：
US15563042
公开号：
US20190365911A1
申请日:
2015.10.14
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention discloses a conjugate constructed by conjugating a HSP90 inhibitory peptide to cytotoxic agent via linker and use thereof in the preparing medicine for preventing and/or treating tumor. The mentioned conjugates possess triple anti-tumor effects including targeting delivery, chemotherapy and apoptosis-promotion, which can enhance the anti-tumor efficacy, reduce the dosage, and decrease the toxicity induced by accumulation of chemotherapeutics.
