Catheter based ablation devices, systems, and methods for achieving intraluminal and/or transluminal neuromodulation, stimulation or ablation by intraluminal access are disclosed herein. One aspect of the present application, for example, is directed to devices, systems, and methods that incorporate a spiral support frame treatment device on an elongate shaft or as a temporary or permanently implanted therapy device. The elongated shaft is sized and configured to deliver a spiral treatment device to a treatment position via an intravascular path. Intraluminal and transluminal neuromodulation, stimulation or ablation or other therapeutic outcomes may be achieved via energy delivered via the spiral element. One therapy includes modulation of neural fibers that contribute to or alter vascular structures that feed or perfuse the neural fibers.
