Eva L. Feldman,Ben Murdock,Stephen Goutman,Stacey Jacoby
申请号:
US16539289
公开号:
US10660895B2
申请日:
2019.08.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are methods for treating, delaying progression of, or reducing the severity of amyotrophic lateral sclerosis (ALS) in a subject through administration of therapeutically effective amounts of agents (e.g., JAK kinase inhibitors (e.g., tofacitinib)) capable of interfering with central nervous system related natural killer cell (NK) levels and function.