The present invention concerns with a new use of R-Bambuterol or Bambuterol as inhaled medicament for treatment of asthma,COPD and other respiratory disorders, and a new use of R-bambuterol or bambuterol and corticosteroids or other therapeutically active medicament as combined inhaled therapies. The invention also related to a new use of R-bambuterol with reduced drug tollerance and risk of exerbation of asthma associated with bambuterol in treatment of respritroy discorders.