Zastosowanie blokera receptora angiotensyny (ARB) oraz inhibitora obojętnej endopeptydazy (NEP) jako składników farmaceutycznych w leczeniu choroby nadciśnieniowej
AL-FAYOUMI, SULIMAN,HU, JIAHUI,KUMARAPERUMAL, NATRAJAN,ROYCE, ALAN EDWARD,RUEGGER, COLLEEN,ZANNOU, ERIKA AINA
申请号：
PL08848154
公开号：
PL2217205T3
申请日:
2008.11.04
申请国别(地区):
PL
年份:
2015
代理人:
摘要：
Solid oral dosage forms, especially tablets, of a pharmaceutical composition comprising a supramolecular complex can be formed from a direct compression process or a compaction process such as roller compaction. Such solid oral dosage forms feature an immediate release profile that allows for fast release of the therapeutic agent. A particularly useful supramolecular complex is trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3'-methyl-2'-(pentanoyl{2"-(tetrazol-5-ylate)biphenyl-4'-ylmethyl}amino)butyrate]hemipentahydrate.
