Chongqing Sun,William R. Ewing,Scott A. Bolton,Zhengxiang Gu,Yanting Huang,Natesan Murugesan,Yeheng Zhu
申请号：
US14005018
公开号：
US20130345123A1
申请日:
2012.03.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein A is a five to eight membered monocyclic or a nine to twelve membered bicyclic heterocyclic ring, as further defined herein Y is S, CH2, or CH Z is CH or N R7 and R9 are hydrogen or (C1-C6)alkyl R2 is (C1-C6)alkoxy, OH, CN, (C1-C6)alkyl, halogen, or CF3 r and s are 0, 1, or 2 and R1 and R3 are as further defined herein. These compounds are agonists, partial agonists and/or modulators of the NPY4 receptor and may be used for the treatment and prophylaxis of obesity, food intake, and other diseases and conditions modulated by the NPY4 receptor.
