KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION;KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL
发明人:
In Kyu Lee,Keun Gyu Park,Chang Joo Oh,Han Jong Kim,Joon-Young Kim
申请号:
US14767767
公开号:
US09724320B2
申请日:
2013.02.20
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a composition for preventing or treating renal fibrosis comprising dimethylfumarate (DMF) as an active ingredient. The DMF according to the present invention has an excellent effect of reducing renal fibrosis by activating Nrf2 to inhibit TGF-β/Smad signaling, and thus is useful for preventing or treating renal fibrosis.