The invention mainly concerns an optical guide for diffusing light radiation through a surface, which is essentially characterised in that it comprises a base (3, 31) comprising or capable of holding at least one diffusion rod (2, 2a; 35a, 35b, 35c), the diffusing bottom end (7, 7a; 38a, 38b, 38c) of which protrudes from said base (3) and is intended to be applied on or close to said surface, and the collecting top end (6, 6a; 37a, 37b, 37c) of which is intended to be situated close to and facing an electrically powered light source (36a, 36b, 36c), and in that the diffusion rod (2, 2a; 35a, 35b, 35c) comprises a material capable of transmitting the light from the collecting end (6, 6a; 37a, 37b, 37c) of same to the diffusing end (7, 7a; 38a, 38b, 38c) of same. The invention also concerns an irradiation module and an irradiation device suitable for transcranial and/or transcutaneous irradiation by light radiation.