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Compositions and methods to inactivate and/or reduce production of microbial toxins
专利权人:
发明人:
Barry Bochner,Xiang-He Lei
申请号:
US14768084
公开号:
US09662372B2
申请日:
2014.02.20
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is related to compositions and methods to treat, ameliorate and/or prevent morbidity and/or mortality from microbial infections. In particular, bacterial infections that are associated with the production and release of bacterial toxins. For example, many Clostridia bacteria, such as Clostridium difficile, release toxins resulting in tissue and organ damage and death, even after antibiotic therapy that either reduces or eliminates the bacteria. In particular, various peptides, polypeptides, and proteins are disclosed herein that either inactivate Clostridium difficile toxin and/or reduce Clostridium difficile toxin production.
来源网站:
中国工程科技知识中心
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