Ho, Wen-Bin,Zhao, Hongda,Deng, Shaojiang,Ng, Danny,Wright, Lee R.,Wu, Min,Zhou, Xiaoti,Arend, Michael P.,Flippin, Lee A.
申请号:
AU2013229922
公开号:
AU2013229922A1
申请日:
2013.03.08
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds of formula (I) for use in disorders such as muscle degeneration, colitis, IBD, and certain ischemias.