Michael Fetell,Richard Malamut,Michael J. Lamson,Ofer Spiegelstein,Yigal Paul Goldberg,Nicola Anne Price
申请号：
US15016921
公开号：
US09682033B2
申请日:
2016.02.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods of treating postherpetic neuralgia in a mammal with a pharmaceutical composition comprising a spiro-oxindole compound of the formula:are disclosed. The methods provide excellent penetration of the spiro-oxindole compound into the affected skin area to effectively reduce the severity of the postherpetic neuralgia and/or to alleviate the postherpetic neuralgia with minimal or negligible systemic exposure of the spiro-oxindole compound.
