THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
KARSENTY GERARD,XIE YULI,DUCY PATRICIA F,LANDRY DONALD W,YADAV VIJAY
申请号：
ZA201007005
公开号：
ZA201007005B
申请日:
2010.10.01
申请国别(地区):
ZA
年份:
2012
代理人:
摘要：
The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPH1 inhibitors or serotonin receptor antagonists.
