Johannes BARTHOLOMÄUS,Anja Geissler,Ulrike BERTRAM,Kornelia GRIESSMANN,Fatima BICANE
申请号:
US16653186
公开号:
US20200038329A1
申请日:
2019.10.15
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, comprisingan opioid (A),a free physiologically acceptable acid (B) in an amount of from 0.001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, anda polyalkylene oxide (C) having a weight average molecular weight Mw of at least 200,000 g/mol.