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Methods for Preparing Injectable Protein Microparticle Suspensions
专利权人:
Ansun Biopharma; Inc.
发明人:
Tiejun Li
申请号:
US14209350
公开号:
US20140342006A1
申请日:
2014.03.13
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method for preparing a microparticle suspension, which comprises: (a) providing protein microparticles having a median diameter between 5 and 13 microns and a GSD less than 2.5; (b) combining the microparticles with a liquid, pharmaceutically acceptable, water miscible media to create a first mixture; (c) adding an aqueous media to the first mixture to create second mixture; and (d) mixing the second mixture to create a microparticle suspension is described. The suspension are injectable even when they contain a relatively high concentration of protein.
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tiejun li
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