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Compositions containing interleukin-1 and peptides
专利权人:
Igor Anatolievich Pomytkin;Igor Arturovic Petropavlov
发明人:
Igor Anatolievich Pomytkin,Igor Arturovic Petropavlov
申请号:
US13124272
公开号:
US08298523B2
申请日:
2008.11.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to pharmaceutical, dermatological, cosmeceutical, or cosmetic compositions comprising (a) interleukin-1 family members consisting of interleukin-1 alpha, interleukin-1 family member 5 (delta), interleukin-1 family member 6 (epsilon), interleukin-1 family member 7 (zeta), interleukin-1 family member 8 (eta), interleukin-1 family member 9, interleukin-1 family member 10 (theta), and interleukin-18; (b) a peptide of the general formula (I): Tyr-X1-X2-Phle-X3-X4-Y, wherein X1 is Gly, L-Ala or D-Ala; X2 is Gly, L-Ala or D-Ala; X3 is absent or independently Leu, Met, Iie, or Val; X4 is absent or independently Ala, Asp, Asn, Glu, Gln, Pro, Arg, Gly, Lys, Thr, or Ser; Y is absent or a sequence of 1 to 5 amino acid residues; and acceptable carriers or diluents.
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