#$%^&*AU2013201147A120130912.pdf#####James & Wells 133072AU/76 ABSTRACT The present invention relates to a composition, the composition including a therapeutically effective amount of at least one active agent, and a base including, an amount of colloidal silica; at least one oil; and at least one surfactant, wherein the viscosity of the composition is below 1000 mPas at a shear rate of 100 1/s and at a temperature of 200C. 40James & Wells 133072AU/76