METHODS FOR OVERCOMING GLUCOCORTICOID RESISTANCE AND FOR DETERMINING GLUCOCORTICOID RESISTANCE POTENTIAL IN CANCER

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专利权人:

发明人:

Steven W. Paugh,William E. Evans,Erik Bonten

申请号：

US15022464

公开号：

US20160230173A1

申请日:

2014.09.16

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene.

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http://www.ckcest.cn/home/