Paul West,Robert E. Burrier,Laura Egnash,Alan Smith,Preeti Bais
申请号：
US14903717
公开号：
US10060932B2
申请日:
2014.07.03
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Methods for identifying metabolic signatures in blood plasma which are unique to autism are described herein. Samples are analyzed using multiple chromatographic-mass spectrometry-based techniques to orthogonally measure a broad range of small molecular weight metabolites differentially produced in autistic patient samples versus non-autistic control samples. These individual metabolites or a panel of such metabolites serve as metabolic signatures of autism. Such metabolic signatures are used in diagnostic methods to accurately identify individuals with autism spectrum disorder (ASD).
