SANTIC, RADMILA,KOPINITS, EDITH,WENINGER, HARALD,MANDLER, MARKUS
申请号:
AU2009257168
公开号:
AU2009257168B2
申请日:
2009.06.12
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention relates to the use of mimotopes in the treatment of &bgr;-Amyloidoses including but not limited to Alzheimer's disease, whereby said mimotopes are able to induce the in vivo formation of antibodies directed to non truncated A&bgr;1-40/42, and N-terminally truncated forms A&bgr;pE3-40/42, A&bgr;3-40/42, A&bgr;11-40/42, A&bgr;pE11-40/42 and A&bgr;14-40/42 without interfering with physiological functions of APP signalling.