SPIROCOMPOSÉS

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专利权人:

F. Hoffmann-La Roche AG

发明人:

申请号：

EP18168269.1

公开号：

EP3556760A1

申请日:

2018.04.19

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention provides compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and alter the substrate specificity of the CRBN E3 ubiquitin ligase complex, resulting in breakdown of intrinsic downstream proteins. Present compounds are thus useful for the treatment of various cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/