The present invention refers to a tubing set 12 suitable for use in co-operation with a hemodialysis machine 10. The tubing set comprises: an out-tube 14 for supplying the blood from the patient to a filter 16 of the machine; an in-tube 18 for supplying the blood from the filter back to the patient; a drip chamber 20 placed along one of said tubes, adapted to let the blood drip through an air buffer 22; and a vial gate 24 for the connection of vials 26 containing drugs to be delivered into the blood. The vial gate 24 according to the invention comprises a delivery lumen 28, suitable for delivering the drug 30 from the vial to the drip chamber, and a vent lumen 32, suitable for providing air 34 inside the vial in order to replace the delivered drug.本發明指的是一種適用於與血液透析機器10協同作用之迴路管12。該迴路管12包括:外管14,用於自病患供血至機器之過濾器16;內管18,用於自該過濾器供血回流至病患;滴注室20,其係沿該等管之一安置,配合成血液經由空氣緩衝器22滴注;以及藥瓶閘口24,用於連接含待輸送至血液中之藥品的藥瓶26。依據本發明之藥瓶閘口24包括:輸送腔28,其適於自藥瓶將藥品30輸送至滴注室;以及排放腔32,其適於將空氣34供入藥瓶26內部以置換已輸送之藥品。