Imidazopirrolidinona derived compounds or their salts, Pharmaceutical composition Crystalline forms； one who understands； and its use for the treatment of a disorder or disease mediated by the activity of MDM2 and / or mdm4 such as proliferative diseases, especially cancer.
The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.COMPUESTOS DERIVADOS DE 5,6-DIHIDRO-1H-PIRROLO[3,4-d]IMIDAZOL-4-ONA O SUS SALES； FORMAS CRISTALINAS DE LOS COMPUESTOS； COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE； Y SU USO PARA EL TRATAMIENTO DE UNA ENFERMEDAD MEDIADA POR LA ACTIVIDAD DE MDM2 Y/O MDM4 TAL COMO CÁNCER.
