SYNAPTOJANIN-2 INHIBITORS FOR USE IN THE TREATMENT OF CANCER

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专利权人:

发明人:

Yosef YARDEN,Nir BEN-CHETRIT

申请号：

US15100322

公开号：

US20170042857A1

申请日:

2014.11.27

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Disclosed herein are synaptojanin-2 inhibitors, and novel methods and uses utilizing same for preventing tumor metastasis, treating cancer or inhibiting synaptojanin-2. Compounds disclosed herein include chlorhexidine and pyrvinium, the compound having the formula:and compounds characterized by the general formula:X-L-[(Y)i-(Z)j]-(L-X)kand/or by the general formula:wherein L, X, Y, Z, D, E, i, j and k are as defined herein.

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