Jacqueline K. Barton,Alexis Komor,Curtis J. Schneider,Alyson Weidmann,Russell Ernst
申请号:
US13511642
公开号:
US08859533B2
申请日:
2012.05.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the inventive metalloinsertor complexes.