The human skin is the outer covering of the body. In humans, it is the largest organ of the integumentary system. Skin type can range from dry to oily. Such skin variety provides a rich and diverse habitat for bacteria which number roughly at 1000 species from 19 phyla. The oily skin is mainly responsible for the formation of acne on the skin. The skin Acne diseases may cause the suicidal case 7% worldwide and 70-80% teenage people is surfing of Acne. 1% clindamycin phosphate and its combination with teritoin and benzoyl peroxide are used to increase the penetration of skin. Clindamycin is water soluble drug and skin is lipophilic in nature so it"s very hard to make direct absorption of drug in the skin. Acnesome = Liposome+Niosomes+Transferosome+ Ethosome. This research has been resized in the form to formulate the Particulate system for the hydrogel topical delivery of the drug so the drug will show longer action in the particular site of inflammation. The drug have been incorporated inside vesicle and provide a control release drug delivery system that provide longer duration of action due to as a transferosome form they will penetrate easily in skin first so no residue on the skin will appear and the drug will accumulate particular site of Action and show its effect in control manner. The ACNESOME provide an elaborative and creative future tactics in the topical preparation in medical and cosmetic preparations by providing change in the formulation o/the vesicular system. The Acnesome has a new platform for the Acne. A novel innovation on the New Drug Delivery System and Control Drug Delivery System which efficaciously safe for the skin, by avoiding unwanted direct use of chemicals on the skin.
