Martyn Frederickson;Miles Stuart Congreve;Christopher William Murray;Gianni Chessari;Eva Figueron Navarro;Alison Jo-Anne Woolford
发明人:
Gianni Chessari,Miles Stuart Congreve,Martyn Frederickson,Christopher William Murray,Eva Figueron Navarro,Alison Jo-Anne Woolford
申请号:
US13271678
公开号:
US20120251545A1
申请日:
2011.10.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides a combination comprising an Hsp90 inhibitor compound of the formula (VII):or tautomer or salt thereof and one or more therapeutic agents selected from topoisomerase I inhibitors; antimetabolites; tubulin targeting agents; DNA binder and topoisomerase II inhibitors; alkylating agents; monoclonal antibodies; anti-hormones; signal transduction inhibitors; proteasome inhibitors; DNA methyl transferases; cytokines; retinoids and HDAC or HAT modulators.