GLAESNER, WOLFGANG,MAYER, JOHN PHILIP,MILLICAN, ROHN LEE JUNIOR,VICK, ANDREW MARK,ZHANG, LIANSHAN
申请号：
CA2608311
公开号：
CA2608311C
申请日:
2006.05.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention provides GLP-1 compounds coupled to two polyethylene glycolmolecule or derivative thereof, resulting in a biologically active peptidewith an extended half-life and a slower clearance when compared to that ofunPEGylated peptide. These PEGylated GLP-1 compounds and compositions areuseful in treating conditions or disorders benefited by lowering bloodglucose, decreasing food intake, decreasing gastric or intestinal emptying,increasing beta (~) cell population, or decreasing gastric or intestinalmotility.
