Improved, portable apparatus for ozone deodorizing and sanitizing of clothing items such as shoes is provided having a housing sized to receive an item to be treated, together with an ozone generator and a ventilation assembly operable to deliver ozone-laden air currents into the housing. In preferred forms, the ozone generator is located within a compartment separate from the housing, and a fan assembly is used to draw ambient air currents adjacent the generator for ozone supplementation, followed by delivery of the ozone-laden air currents into the housing.