DEXTER A. CHISHOLM,MARK S. PAYNE,PIERRE E. ROUVIERE,HONG WANG,SCOTT D. CUNNINGHAM,ROBERT DICOSIMO,KARI A. FOSSER,TANJA MARIA GRUBER,XUEPING JIANG,ANJU PARTHASARATHY
申请号：
US13523392
公开号：
US20130171217A1
申请日:
2012.06.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed herein are compositions and methods to treat skin with a peracid-based benefit agent. The peracid benefit agent can be used for a benefit such as the prevention or treatment of acne, skin whitening, skin bleaching, skin conditioning, reducing the appearance of skin wrinkles, skin rejuvenation, reducing dermal adhesions, and preventing, reducing or eliminating body odors or any combination thereof. The peracid may be enzymatically generated from a carboxylic acid ester substrate using an enzyme having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a skin-binding domain, either directly or through an optional linker, may be used to target the perhydrolytic activity to the skin surface.
