Fused heterocyclic derivatives and uses thereof

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专利权人:

武田薬品工業株式会社

发明人:

藤井 伸寛,大黒 裕哉,佐々木 聡,近藤 滋

申请号：

JP2011022188

公开号：

JP5490030B2

申请日:

2011.02.03

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention provides a compound having a superior Smo inhibitory activity and lower toxicity, which is sufficiently satisfactory as a pharmaceutical product. The present invention provides a compound represented by the formula wherein ring A is 5- to 7-membered ring optionally having substituent(s), where substituents are optionally bonded to each other to form a ring； X is O, S or NR1 (R1 is a hydrogen atom or a hydrocarbon group optionally having substituent(s))； R2 is carbamoyl optionally having substituent(s)； and R3 is hydroxy optionally having substituent(s), or a salt thereof.

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