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METHOD OF PRODUCING A GRANULATED COMPOSITION
专利权人:
Cubic Pharmaceuticals Ltd.;Delta Pharmaceuticals Ltd.
发明人:
Dennis Douroumis,Mohammed Maniruzzaman,Saumil Kiritkumar Bhatt,Anwar Ali,Arun Jangra
申请号:
US15549880
公开号:
US20180015040A1
申请日:
2016.02.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method of producing an extruded, powdered/granulated composition comprising an active pharmaceutical ingredient (API), by the steps of providing an API and a porous inorganic excipient, and processing them by an extrusion process to directly produce an extruded, powdered/granulated composition wherein the API is at least partially absorbed within the pores of the inorganic excipient. In preferred embodiments, the API is melted, or solubilised in a solubilizer.
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