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Derivatives of pyrroloimidazole or analogues thereof which are useful for the treatment of inter alia cancer
专利权人:
Emcure Pharmaceuticals Limited
发明人:
Gurjar, Mukund Keshav,Roychowdhury, Abhijit,Khaladkar, Tushar Pandurang,Sawargave, Sangmeshwar Prabhakar,Janrao, Ravindra Ashok,Kalhapure, Vijay Keshav,Urunkar, Ganesh Devidas,Gullapalli, Srinivas,Kul
申请号:
AU2017215424
公开号:
AU2017215424A1
申请日:
2017.01.31
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Present invention relates to novel heterocyclic compounds as indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) modulators. Compounds of the present invention inhibit tryptophan degradation by modulating IDO and/or TDO. Formula (I) The invention further relates to the process of their preparation, pharmaceutical composition and their use in modulating the activity of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3- dioxygenase (TDO). The compounds of the invention can be used alone or in combination for the treatment of conditions that benefits from the inhibition of tryptophan degradation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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