Kevin J. Tracey,Howland Shaw Warren,Michael Allen Faltys
申请号：
US12048114
公开号：
US20160250097A9
申请日:
2008.03.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Described herein are devices, systems and method for treating inflammatory disorders by modulating a subjects inflammatory reflex. The method may include the step of non-invasively stimulating the inflammatory reflex (e.g., the vagus nerve, the splenic nerve, the hepatic nerve, the facial nerve, and the trigeminal nerve) of a subject in a manner which significantly reduces proinflammatory cytokines in the subject and/or provides a therapeutically effective treatment for the subject. Devices for non-invasively stimulating the inflammatory reflex may include a movable tip or actuator that is controlled to mechanically stimulate the ear. The devices may be hand-held or wearable, and may stimulate the cymba conchae region of the subjects ear.
