ЭТО Кодзи (JP),ОХНИСИ Риоко (JP),НАКАУТИ Хиромицу (JP),МУРАТА Такахико (JP)
申请号：
RU2013117422/04
公开号：
RU2013117422A
申请日:
2011.09.16
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A composition for maintenance of platelet function, wherein the composition comprises as active ingredient contains a compound represented by the following general formula (I), or a salt or solvate thereof: gdeX represents a phenylene group Y represents any of a hydrogen atom and - ( CH) R gdem represents any integer from 0 to 4 iRpredstavlyaet be any izgde R is any alkyl group from C1 to C6, which may be substituted, an aryl group which may be substituted, an alkoxy group of C1 to C6 each of R independently represents any of hydrogen atom and alkyl groups from C1 to C6, or R Rvmeste with the adjacent nitrogen atom may form a nitrogen-containing heterocycle iRpredstavlyaet is any of hydrogen atom, an alkyl group from C1 to C6 alkylsulfonyl group and from C1 to C6 and Z is any of hydrogen atom and alkyl groups from C1 to C6.2. A composition according to claim 1, wherein the compound represented by the general formula (I), represents any izN- [2- (4-but-2-iniloksibenzolsulfonil) -1- (4-dietilaminometilfenil) ethyl] -N-hydroxyformamide and N- { 4- [2- (4-but-2-iniloksibenzolsulfonil) -1- (formilgidroksiamino) ethyl] benzyl} metansulfonamida.3. A composition according to any one of claims 1 and 2 in the form of any of the reactant to maintain platelet function and additives to a blood preparation containing trombotsity.4. A method of producing platelets, wherein the method comprises adding to the culture system for megakaryocyte differentiation of cells able to differentiate into megakaryocytes and platelets from megakaryocytes obtain a compound represented by the following general formula (I), or a salt thereof, or1. Композиция для поддержания функции тромбоцитов, где композиция в качестве активного ингредиента содержит соединение, представленное приведенной ниже общей формулой (I), или его соль, или его сольват:гдеX представляет собой фениленовую группуY представляет собой любой из атома водорода и -(CH2)mR1гдеm представляет собой любое целое число от 0 до 4 иR1 пр
