The invention proposes an In-situ Sensor (1) for being implanted within tissue of a mammal (P) comprising • an energy harvesting portion (RX), • a communication portion (TX), • a pressure sensor (SP) for measuring interstitial pressure of surrounding tissue when located within tissue, • a further sensor (SF), whereby the further sensor is selected from a group comprising pH sensor, lactate sensor, impedance sensor, radiation sensor, temperature sensor, sensor for bioelectrical potentials, • whereby said further sensor (SF), said pressure sensor (SP) as well as the communication portion (TX) are powered by the energy harvesting portion (RX), • whereby information indicative of the measurement provided by the pressure sensor (SP) and data indicative of the measurement provided by said further sensor (SF) is communicated via said communication portion (TX) towards an extracorporeal receiving entity (ECE). Fig. 3 93109
