The present invention relates to at least one active component belonging to an active component group Dr having at least a respiration inhibiting side effect, and a nose of at least one active component belonging to an active component group ADR that is capable of being induced by an active component of Dr group The present invention relates to an intracoronary continuous administration system. The present invention further relates to a portable medical device for continuous use in nasal cavity which incorporates an nasal cavity system according to the principles of the present invention. Diagram本発明は、少なくとも呼吸抑制副作用を有する活性成分群DRに属する少なくとも1つの活性成分と、DR群の活性成分によって誘発され得る呼吸抑制に対抗する活性成分群ADRに属する少なくとも1つの活性成分の鼻腔内連続投与システムに関する。本発明は、さらに、本発明の原理による鼻腔内投与システムを内蔵する鼻腔内連続投与用携帯型医療装置に関する。【選択図】図1