Wiggington, Jon Marc,Pandya, Naimish Bharat,Lechleider, Robert Joseph,Koenig, Scott,Bonvini, Ezio
申请号：
AU2016276706
公开号：
AU2016276706A2
申请日:
2016.06.09
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
This invention relates to a pharmaceutical composition that comprises a first molecule that specifically binds HER2/neu and a second molecule that specifically binds a cell-surface receptor (or its ligand) that is involved in regulating an immune checkpoint (or the ligand thereof). The invention particularly relates to the embodiment wherein the second molecule binds to PD-1. The invention also relates to the use of such pharmaceutical compositions to treat cancer and other diseases.
