THIADIAZOLIDINONES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF FOR THE MANUFACTURE OF A MEDICAMENT

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专利权人:

NOSCIRA; S.A.

发明人:

申请号：

IL17812506

公开号：

IL178125A

申请日:

2006.09.14

申请国别(地区):

IL

年份:

2012

代理人:

摘要：

Provided arc thiadiazolidinc compounds of formula I <；CHEM>； wherein R1 is an organic group having at least 8 atoms selected from C or O, which is not linked directly to the N through a -C(O)- and comprising at least an aromatic ring, and their pharmaceutical compositions. These compounds are selective GSK-3 inhibitors and have improved bioavailability. They are useful for the treatment of GSK-3 mediated diseases, among others Alzheimer's disease, type II diabetes, depression and brain injury.

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中国工程科技知识中心

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