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Method for selecting or preferentially recovering genes or gene products containing long chain repeats
专利权人:
公益財団法人ヒューマンサイエンス振興財団
发明人:
北條 浩彦,高橋 理貴
申请号:
JP2009283653
公开号:
JP5716217B2
申请日:
2009.12.15
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
<;P>;PROBLEM TO BE SOLVED: To provide a method for selecting or preferentially collecting a gene or gene product including a long chain-repeating sequence such as a variant allele that has a long repeating sequence and causes diseases more than a gene or gene product having a short chain-repeating sequence such as a normal allele having a short repeating sequence. <;P>;SOLUTION: The method for selecting or preferentially collecting a gene or gene product including a long chain-repeating sequence includes processes of: (a) a process of hybridizing a synthetically labelled RNA probe including a repeating sequence in the base sequence of a sense chain or antisense chain of gene to genomic DNA obtained from a living body, all RNA or cDNA synthesized from the all RNA; and (b) a process of collecting and purifying a conjugate between DNA or RNA obtained in the process (a) and the synthetically labelled RNA probe on the basis of the label. <;P>;COPYRIGHT: (C)2011,JPO&INPIT
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中国工程科技知识中心
来源网址:
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