Provided is a prophylactic and/or therapeutic agent for fungal eye infection or acanthamoeba eye infection, said prophylactic and/or therapeutic agent comprising an azole antifungal agent as an active ingredient, characterized in that the azole antifungal agent is administered to the eyelid skin.本發明提供一種含有唑系抗真菌藥作為有效成分之真菌性眼感染症或棘阿米巴性眼感染症之預防及/或治療劑,其特徵為將唑系抗真菌藥投與至眼瞼皮膚。